DAAM1 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comDAAM1 Polyclonal Antibody for Human(Homo sapiens)

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DAAM1 (Gene name),

Disheveled-associated activator of morphogenesis 1 (Protein name ), DAAM1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

DAAM1(KIAA0666);

Protein name:

Disheveled-associated activator of morphogenesis 1;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer. Interacts with CIP4, FNBP1 and FNBP1L. Interacts with the SH3 domains of Abl, BTK, endophilin, spectrin and SRC. Binds specifically to GTP-bound CDC42 and RHOA.

Function:

Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments.

Subcellular Location:

Cytoplasm Perinuclear.

Protein Attributes:

Sequence length:

1078

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1078:

SKLKRNRKRI | TNQMTDSSRE | RPITKLNF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.19156

SMR:

Q9Y4D1

Pfam:

PF06367

String:

Q9Y4D1

MIM:

606626

UniGene:

Hs.654934

KEGG:

hsa:23002

STRING:

9606.ENSP00000247170

Uniprot:

Q9Y4D1

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ELISA Kit for Human Disheveled-associated activator of morphogenesis 1

Cat.:

E15379h

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96T

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ELISA Kit for Human Disheveled-associated activator of morphogenesis 1

Cat.:

E15379m

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Manual:

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MSDS:

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Packing:

96T

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CLIA Kit for Human Disheveled-associated activator of morphogenesis 1

Cat.:

U15379h

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MSDS:

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Packing:

96T

CLIA Kit for Human Disheveled-associated activator of morphogenesis 1

Cat.:

U15379m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Disheveled-associated activator of morphogenesis 1

Cat.:

P15379Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Disheveled-associated activator of morphogenesis 1

Cat.:

P15379Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Disheveled-associated activator of morphogenesis 1

Protein for Human Disheveled-associated activator of morphogenesis 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
Ishikawa K. , Nagase T. , Suyama M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
DNA Res.5:169-176(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
2.

"The DNA sequence and analysis of human chromosome 14."
Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Placenta.
tissue: Uterus.
4.

"Full-length cDNA libraries and normalization."
Li W.B. , Gruber C. , Jessee J. , Polayes D.
Submitted (2003-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-497 (ISOFORM 1)
tissue: Fetal brain.
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 706-1078 (ISOFORM 3)
tissue: Thymus.
6.

"Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1."
Habas R. , Kato Y. , He X.
Cell107:843-854(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
7.

"The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics."
Aspenstroem P. , Richnau N. , Johansson A.-S.
Exp. Cell Res.312:2180-2194(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ABL1; BTK; CDC42; CIP4; ENDOPHILIN; FNBP1; FNBP1L; RHOA; SPECTRIN AND SRC;SUBCELLULAR LOCATION
8.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.

"Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly."
Lu J. , Meng W. , Poy F. , Maiti S. , Goode B.L. , Eck M.J.
J. Mol. Biol.369:1258-1269(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS) OF 596-1078;SUBUNIT;MUTAGENESIS OF ILE-698;FUNCTION

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